Coronavirus COVID-19 (SARS-CoV-2) Antibody Test Kit

$550 per kit

Each kit tests up to 152 individuals

Volume Discounts Available

The IONTOX Coronavirus COVID-19 (SARS-CoV-2) Antibody Test Kit is an ELISA based kit that allows hospitals, academic institutions, and laboratories to screen for Coronavirus antibodies. The test kit was developed in collaboration with the Western Michigan University Homer Stryker M.D. School of Medicine to help protect health care workers during the Coronavirus outbreak.

Specifications

COVID-19 (SARS-CoV-2) Antibody Test Kit Background

In early 2020, Western Michigan University Homer Stryker M.D. School of Medicine contacted IONTOX, LLC to develop a sensitive and highly versatile SARS-CoV-2 antibody serological test. The result of this collaboration is an ELISA test that and allows clinical laboratories to screen for both the receptor binding domain (RBD) and the full spike protein. The test was developed using blood collected from pre-pandemic, COVID negative and those individuals who had COVID-19 and recovered. Samples from this latter group were collected 14 days after they tested negative for the virus (e.g. recovered). The company has completed a double blinded study and received a score of 100%. This means 100% sensitivity and specificity. The IONTOX test is specific for SARS-CoV-2. The test has outperformed both the Roche and Abbot tests and is considerably more informative. The test provides significant flexibility for test laboratories in that the ELISA plates have removable wells. The test also provides antibodies to IgG and IgM immunoglobulins. The test also enables testing laboratories and researchers to quantify SARS-CoV-2 antibody titer. This information is essential for understanding what stage of the disease the patient was in and for tracking population immunity (epidemiology). FDA approval is expected by July 2020.

Advantages of the IONTOX COVID-19 (SARS-CoV-2) Antibody Test Kit

What Comes In Each COVID-19 (SARS-CoV-2) Antibody Test Kit

What You Need In Your Facility

Test Results and Clinical Significance

This procedure was developed as a two-stage ELISA in which the first stage includes relatively high-throughput screening of samples in a single serum dilution against the RBD (which expresses well and therefore can be produced in greater quantities). This is followed by a second stage in which positive samples from the first stage are subjected to a confirmatory ELISA against the full-length spike protein (which is harder to express and is less available). For the second stage, a dilution curve is performed.

Samples that exceed a specified optical density cutoff value (cutoff: optical density = 0.15 to 0.2) are assigned as presumptive positives and will be tested in the confirmatory ELISA using full-length spike protein. The OD490 cutoff must be experimentally determined in each testing laboratory and depends on assay background and noise.

The ability to quantify IgG and IgM levels with SARS II Antibody allows the accumulation of important immunological data and immunity tracking in various populations.

The IONTOX Coronavirus COVID-19 (SARS-CoV-2) Antibody Test Kit is ELISA test kit that allows hospitals, academic institutions, and CLIA Certified Laboratories screen for Coronavirus antibodies. The test kit was developed in collaboration with the Western Michigan University Homer Stryker M.D. School of Medicine to help protect health care workers during Coronavirus outbreak.

Specifications