Every new drug candidate must undergo an Investigational New Drug (IND) application before it can be administered in human clinical trials. The IND application is submitted to the Food and Drug Administration (FDA). It includes several assays known as IND-enabling studies that prove the drug candidates potency and safety for humans.
In this blog post, we’ll explain what ADME stands for, and how ADME and toxicology assays work. We’ll also go into more detail about their importance to the pharmaceutical industry, and explain the in vitro testing capabilities at IonTox.
IONTOX LLC, located in the BTR Park’s WMed Innovation Center, was recently named a Best Small Business by the Michigan Economic Development Corp. during its annual Michigan Celebrates Small Business awards celebration which was held virtually on July 28.
On Thursday, August 24th at 10:00 AM IONTOX president Jim Mckim, will participate in an oral presentation at the 10th World Congress on Alternatives and Animals in the Life Sciences with our partner company Qualyst Transporter Solutions on new methods for predicting drug-induced liver toxicity and integrated multiple organ test systems. Presentation Information: Abstract Number: […]
From Saturday, March 11th to March 15th IONTOX founder Toxicologist Jim Mckim, and Director of Laboratory Services Nick Hibbard will be at the Annual Society of Toxicology meeting in Baltimore, Maryland. IONTOX, is a CRO specializing the development of new in vitro models for new molecular entity testing. The company’s latest development includes a Multiple Organ […]
Three common additives to cell culture media are the beta-lactam family of antibiotics (penicillin), aminoglycosides family of antibiotics (streptomycin), and the antifungal family polyene macrolides (amphotericin B). Penicillin, streptomycin, andamphotericin B are often added to culture media to prevent unwanted contamination in the culture. However, overuse of antibiotics and antifungals can mask serious problems including mycoplasma […]
24 November 2016 US-based biotech company IONTOX and British American Tobacco have entered into a collaboration to develop a lung-liver-lung model with a simulated blood system to study the impact of tobacco and nicotine products on lung health. Cigarette smoking is associated with a number of diseases that can impact the lung, such as cancer […]