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About IONTOX


IONTOX works with a global client base on ADME-PK and toxicology based in vitro research.


In 2013 the Editor and Chief of Applied In Vitro Toxicology James McKim, Ph.D., D.A.B.T., founded IONTOX to support his contacts in the pharmaceutical, chemical, food additive, and cosmetic industries.


IONTOX is fully GLP compliant and follows all OECD, GIVIMP, GCCP guidelines.







Proprietary Technology


An in vitro system for understanding compound drug and chemical movement in multiple organs.

Using the Human Dynamic Multiple Organ Plate (HuDMOP)TM gives clients the ability to integrate two to six organ systems when running in vitro studies.




ADME -PK In Vitro


Study Absorption, distribution, metabolism, excretion, and pharmacokinetics.

IND Enabling

Assays required by the FDA for an investigational new drug.

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New Chemical Registration

Assays to support research for New Chemical Registration.

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Standard ADME-PK

Gold standard assays for understanding the ADME of a compound.

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Cytotoxicity


Study cell toxicity

Cell Viability

Assays to identify cell viability.

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Mitotoxicity

Assay to assess mitochondrial toxicity.

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Cytotoxicity Panel

Assays for in vitro to in vivo extrapolation.

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Advanced In Vitro Research


Do advanced in vitro research

Organ Specific Toxicity

Identify adverse outcome pathways of a specific organ in vitro.

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IDILI Liability

Understand a compounds liability to cause idiosyncratic drug injury.

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Multiple Organ Studies

Link organ models together to understand systemic toxicity.

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3D Tissue Testing


Study how your compound effects advanced 3D tissue models.

Ocular Irritation

Screen compounds for ocular irritation with advanced 3D models.

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Dermal Irritation

Screen compounds for dermal irritation with advanced 3D models.

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Dermal Corrosion

Screen compounds for dermal corrosion with advanced 3D models.

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Contact Us


A biotechnology company founded in 2014, dedicated to providing expertise to the area of in vitro toxicology. IONTOX operates during business hours from Monday to Friday (8:00 AM - 5:00 PM Eastern Standard Time).

For all calls or emails, please allow one business day for response.

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